Research Opportunities

Bioo Scientific - Chemist

SBIR Award Title

SBIR Phase II: Improved in Vivo Delivery of SiRNA

SBIR Award Abstract

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Innovation Research (SBIR) Phase II project will develop technologies that optimize the use of RNA interference (RNAi) in animals. RNAi is an invaluable tool for characterizing gene function and is a promising candidate for gene therapy. The use of RNAi in tissue culture is well developed but is of limited use in experimental animals. RNAi agents must enter cells to exert their effects but this has prov... more

Research Opportunity



3913 Todd Lane Suite 312


Sam Sun

Principal Investigator

Sam Sun


Major responsibilities
The role of the Staff Scientist will include conjugation of antibodies to positively charged protein carriers, conjugation of small molecules and nucleic acids to delivery vehicles. A good understanding of protein purification and formulation development and analytical methods is a plus. This position will be primarily supported through a National Science Foundation Small Business Innovation Research Grant. The Staff Scientist will also be encouraged to write SBIR grants, develop intellectual property and manufacture products. Experience developing, establishing, and validating analytical test methods for raw materials, production intermediates, and final products and transferring validated protocols to production is a plus. The successful candidate should have a Ph.D. in Chemistry with 0 - 3 years of relevant industrial experience. Excellent communication, interpersonal, and organizational skills and a strong desire to work in a challenging and dynamic interdisciplinary environment are required.

Desired Knowledge

Preferable Attributes:
· Articulate
· Self-motivated
· Highly focused
· Strong multi-tasking skills
· Strong initiative
· Strong communication skills
· Good problem solver
· Works well individually as well as within a team
· Positive attitude